Heterogeneity of regional inflection points from pressure-volume curves assessed by electrical impedance tomography.

ABSTRACT:

Background

The pressure-volume (P-V) curve has been suggested as a bedside tool to set mechanical ventilation; however, it reflects a global behavior of the lung without giving information on the regional mechanical properties. Regional P-V (PVr) curves derived from electrical impedance tomography (EIT) could provide valuable clinical information at bedside, being able to explore the regional mechanics of the lung. In the present study, we hypothesized that regional P-V curves would provide different information from those obtained from global P-V curves, both in terms of upper and lower inflection points. Therefore, we constructed pressure-volume curves for each pixel row from non-dependent to dependent lung regions of patients affected by acute hypoxemic respiratory failure (AHRF

SUBMITTER: Scaramuzzo G 

PROVIDER: S-EPMC6469223 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature