Chronic kidney disease in patients infected with human immunodeficiency virus (HIV) in an urban cohort.

ABSTRACT:

Background and objectives

HIV-infected patients are at risk for developing chronic kidney disease (CKD), defined by estimated glomerular filtration rate (eGFR) <60 ml/min/1.73m2. Our purpose was to understand the genesis of CKD in HIV patients from a large urban clinic in Houston, Texas, USA, and to characterize progression of CKD in the cohort.

Design, setting, participants and measurements

A retrospective cohort study (2012-2016) was conducted in all HIV-infected patients seen in a federally qualified community health center in Houston, Texas. CKD prevalence and its association with HIV viral load and CD4 count were determined. The association of the change in eGFR over time and comorbidities was assessed using linear mixed models.

Results

Of 3714 HIV-infected patie

SUBMITTER: Brito RM 

PROVIDER: S-EPMC6469809 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature