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Altered lateralization of dorsal language tracts in 6-week-old infants at risk for autism.


ABSTRACT: Altered structural connectivity has been identified as a possible biomarker of autism spectrum disorder (ASD) risk in the developing brain. Core features of ASD include impaired social communication and early language delay. Thus, examining white matter tracts associated with language may lend further insight into early signs of ASD risk and the mechanisms that underlie language impairments associated with the disorder. Evidence of altered structural connectivity has previously been detected in 6-month-old infants at high familial risk for developing ASD. However, as language processing begins in utero, differences in structural connectivity between language regions may be present in the early infant brain shortly after birth. Here we investigated key white matter pathways of the dorsal la

SUBMITTER: Liu J 

PROVIDER: S-EPMC6470045 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature