Comprehensive Preterm Breast Milk Metabotype Associated with Optimal Infant Early Growth Pattern.

ABSTRACT: Early nutrition impacts preterm infant early growth rate and brain development but can have long lasting effects as well. Although human milk is the gold standard for feeding new born full-term and preterm infants, little is known about the effects of its bioactive compounds on breastfed preterm infants' growth outcomes. This study aims to determine whether breast milk metabolome, glycome, lipidome, and free-amino acids profiles analyzed by liquid chromatography-mass spectrometry had any impact on the early growth pattern of preterm infants. The study population consisted of the top tercile-Z score change in their weight between birth and hospital discharge ("faster grow", n = 11) and lowest tercile ("slower grow", n = 15) from a cohort of 138 premature infants (27⁻34

SUBMITTER: Alexandre-Gouabau MC 

PROVIDER: S-EPMC6470768 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature