Sensing by Molecularly Imprinted Polymer: Evaluation of the Binding Properties with Different Techniques.

ABSTRACT: The possibility of investigating the binding properties of the same molecularly imprinted polymer (MIP), most probably heterogeneous, at various concentration levels by different methods such as batch equilibration and sensing, is examined, considering two kinds of sensors, based respectively on electrochemical and surface plasmon resonance (SPR) transduction. As a proof of principle, the considered MIP was obtained by non-covalent molecular imprinting of 2-furaldehyde (2-FAL). It has been found that different concentration ranges of 2-FAL in aqueous matrices can be measured by the two sensing methods. The SPR sensor responds in a concentration range from 1 × 10-4 M down to about 1 × 10-7 M, while the electrochemical sensor from about 5 × 10-6 M up to about 9 × 10-3 M. The binding isotherm

SUBMITTER: Pesavento M 

PROVIDER: S-EPMC6470915 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature