Eradication therapy for Burkholderia cepacia complex in people with cystic fibrosis.

ABSTRACT:

Background

Chronic infection with Burkholderia cepacia complex species remains a significant problem for clinicians treating people with cystic fibrosis. Colonisation with Burkholderia cepacia complex species is linked to a more rapid decline in lung function and increases morbidity and mortality. There remain no objective guidelines for strategies to eradicate Burkholderia cepacia complex in cystic fibrosis lung disease, as these are inherently resistant to the majority of antibiotics and there has been very little research in this area. This review aims to examine the current treatment options for people with cystic fibrosis with acute infection with Burkholderia cepacia complex and to identify an evidence-based strategy that is both safe and effective. This is an updated version

SUBMITTER: Regan KH 

PROVIDER: S-EPMC6471232 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature