Generation of engineered core-shell antibiotic nanoparticles.

ABSTRACT: Well-defined nanocomposite structures have received significant attention due to their superior combinatorial properties. Rational tuning of the core and shell of the nanostructure(s) can offer potent antibacterial activity. Such advanced core-shell nanocomposite methodologies allow not only the incorporation of antibacterial agents on the shell but also provide its stability and nurture antibacterial activity. Herein, antibiotic zinc oxide-curcumin (ZnO-Cum) core-shell nanoparticles for antibacterial application were synthesised. The ZnO-Cum core-shell nanoparticles were prepared by curcumin nanolayer deposition on zinc oxide nanoparticles via a sonication process. The resulting ZnO-Cum core-shell nanoparticles were spiracle in shape with a ∼45 nm ZnO core and ∼12 nm curcumin shell

SUBMITTER: Varaprasad K 

PROVIDER: S-EPMC6472438 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature