Wide sensory filters underlie performance in memory-based discrimination and generalization.

ABSTRACT: The way animals respond to a stimulus depends largely on an internal comparison between the current sensation and the memory of previous stimuli and outcomes. We know little about the accuracy with which the physical properties of the stimuli influence this type of memory-based discriminative decisions. Research has focused largely on discriminations between stimuli presented in quick succession, where animals can make relative inferences (same or different; higher or lower) from trial to trial. In the current study we used a memory-based task to explore how the stimulus' physical properties, in this case tone frequency, affect auditory discrimination and generalization in mice. Mice performed ad libitum while living in groups in their home quarters. We found that the frequency distance be

SUBMITTER: Chen C 

PROVIDER: S-EPMC6472767 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature