Night work during pregnancy and preterm birth-A large register-based cohort study.

ABSTRACT:

Background

Melatonin stimulates the production of progesterone, which is essential for the maintenance of pregnancy. Since melatonin in blood is reduced due to work under illuminated conditions during night work, it has been hypothesized that night work may increase the risk of preterm birth. Previous meta-analyses have not revealed increased risk of preterm birth in women working night shifts during pregnancy. Still, these studies might have been limited by inaccurate self-reports of timing, intensity and duration of night work most likely causing bias towards the null. The aim of this is study was to investigate if the frequency and duration of night work during the first (week 1-12) and second (week 13-22) trimester of pregnancy were associated with risk of preterm birth when ob

SUBMITTER: Specht IO 

PROVIDER: S-EPMC6472821 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature