Formulation and Characterization of a SIS-Based Photocrosslinkable Bioink.

ABSTRACT: Decellularized extracellular matrices (dECMs) represent a promising alternative as a source of materials to develop scaffolds that closely mimic the native environment of cells. As a result, dECMs have attracted significant attention for their applications in regenerative medicine and tissue engineering. One such application is 3D bioprinting, in which dECMs can be used to prepare bioinks with the biomimicry attributes required for regeneration purposes. Formulating bioinks is, however, challenging, due to difficulties in assuring that the printed materials match the mechanical properties of the tissue which is to be regenerated. To tackle this issue, a number of strategies have been devised, including crosslinking methods, the addition of synthetic materials as excipients, and the use of

SUBMITTER: Serna JA 

PROVIDER: S-EPMC6473614 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature