Physical Interactions Strengthen Chemical Gelatin Methacryloyl Gels.

ABSTRACT: Chemically cross-linkable gelatin methacryloyl (GM) derivatives are getting increasing attention regarding biomedical applications. Thus, thorough investigations are needed to achieve full understanding and control of the physico-chemical behavior of these promising biomaterials. We previously introduced gelatin methacryloyl acetyl (GMA) derivatives, which can be used to control physical network formation (solution viscosity, sol-gel transition) independently from chemical cross-linking by variation of the methacryloyl-to-acetyl ratio. It is known that temperature dependent physical network formation significantly influences the mechanical properties of chemically cross-linked GM hydrogels. We investigated the temperature sensitivity of GM derivatives with different degrees of modification

SUBMITTER: Rebers L 

PROVIDER: S-EPMC6473781 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature