Analysis of the Bacterial and Host Proteins along and across the Porcine Gastrointestinal Tract.

ABSTRACT: Pigs are among the most important farm animals worldwide and research to optimize their feed efficiency and improve their welfare is still in progress. The porcine intestinal microbiome is so far mainly known from sequencing-based studies. Digesta and mucosa samples from five different porcine gastrointestinal tract sections were analyzed by metaproteomics to obtain a deeper insight into the functions of bacterial groups with concomitant analyses of host proteins. Firmicutes (Prevotellaceae) dominated mucosa and digesta samples, followed by Bacteroidetes. Actinobacteria and Proteobacteria were much higher in abundance in mucosa compared to digesta samples. Functional profiling reveals the presence of core functions shared between digesta and mucosa samples. Protein abundances of energy pro

SUBMITTER: Troscher-Mußotter J 

PROVIDER: S-EPMC6473940 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature