Self-Powered Well-Aligned P(VDF-TrFE) Piezoelectric Nanofiber Nanogenerator for Modulating an Exact Electrical Stimulation and Enhancing the Proliferation of Preosteoblasts.

ABSTRACT: Electric potential plays an indispensable role in tissue engineering and wound healing. Piezoelectric nanogenerators based on direct piezoelectric effects can be self-powered energy sources for electrical stimulation and have attracted extensive attention. However, the accuracy of piezoelectric stimuli on piezoelectric polymers membranes in vitro during the dynamic condition is rarely studied. Here, a self-powered tunable electrical stimulation system for assisting the proliferation of preosteoblasts was achieved by well-aligned P(VDF-TrFE) piezoelectric nanofiber membrane (NFM) both as a nanogenerator (NG) and as a scaffold. The effects of electrospinning and different post-treatments (annealing and poling) on the surface wettability, piezoelectric β phase, ferroelectric properties, and s

SUBMITTER: Wang A 

PROVIDER: S-EPMC6473961 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature