Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review protocol.

ABSTRACT:

Background and purpose

Cerebral venous thrombosis causes disability from venous infarct and hemorrhage and potential mortality. Anticoagulation improves survival and disability outcomes, yet direct oral anticoagulants are currently not indicated in cerebral venous thrombosis due to lack of evidence, despite being on the market for nearly a decade. This systematic review will collate evidence of reported safety and efficacy of direct oral anticoagulant therapy in cerebral venous thrombosis.

Methods

A search strategy was developed with a research librarian and registered on a protocol database (PROSPERO CRD42017078398). All published studies from MEDLINE and EMBASE up to February 2019 containing patients diagnosed with cerebral venous thrombosis who were treated with a direct

SUBMITTER: Bose G 

PROVIDER: S-EPMC6474061 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature