Characterization of putative proteins encoded by variable ORFs in white spot syndrome virus genome.

ABSTRACT:

Background

White Spot Syndrome Virus (WSSV) is an enveloped double-stranded DNA virus which causes mortality of several species of shrimp, being considered one of the main pathogens that affects global shrimp farming. This virus presents a complex genome of ~ 300 kb and viral isolates that present genomes with great identity. Despite this conservation, some variable regions in the WSSV genome occur in coding regions, and these putative proteins may have some relationship with viral adaptation and virulence mechanisms. Until now, the functions of these proteins were little studied. In this work, sequences and putative proteins encoded by WSSV variable regions were characterized in silico.

Results

The in silico approach enabled determining the variability of some sequences, as

SUBMITTER: de Macedo Mendes C 

PROVIDER: S-EPMC6474068 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature