FDG PET based prediction of response in head and neck cancer treatment: Assessment of new quantitative imaging features.

ABSTRACT:

Introduction

18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is now a standard diagnostic imaging test performed in patients with head and neck cancer for staging, re-staging, radiotherapy planning, and outcome assessment. Currently, quantitative analysis of FDG PET scans is limited to simple metrics like maximum standardized uptake value, metabolic tumor volume, or total lesion glycolysis, which have limited predictive value. The goal of this work was to assess the predictive potential of new (i.e., nonstandard) quantitative imaging features on head and neck cancer outcome.

Methods

This retrospective study analyzed fifty-eight pre- and post-treatment FDG PET scans of patients with head and neck squamous cell cancer to calculate five standard and seventeen n

SUBMITTER: Beichel RR 

PROVIDER: S-EPMC6474600 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature