Statin Therapy Before Transition to End-Stage Renal Disease With Posttransition Outcomes.

ABSTRACT: Background Although studies have shown that statin therapy in patients with non-dialysis-dependent chronic kidney disease was associated with a lower risk of death, this was not observed in dialysis patients newly initiated on statins. It is unclear if statin therapy benefits administered during the predialysis period persist after transitioning to end-stage renal disease. Methods and Results In 47 720 veterans who transitioned to end-stage renal disease during 2007 to 2014, we examined the association of statin therapy use 1 year before transition with posttransition all-cause and cardiovascular mortality and hospitalization incidence rates over the first 12 months of follow-up. Associations were examined using multivariable adjusted Cox proportional hazard models and negative binomial re

SUBMITTER: Soohoo M 

PROVIDER: S-EPMC6475049 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature