Incidence of second and higher order smoking-related primary cancers following lung cancer: a population-based cohort study.

ABSTRACT:

Background

Lung cancer 5-year survival has doubled over 15 years. Although the risk of second primary cancer is recognised, quantification over time is lacking. We describe the incidence of second and higher order smoking-related primary cancers in lung cancer survivors, identifying high-incidence groups and how incidence changes over time from first diagnosis.

Methods

Data on smoking-related primary cancers (lung, laryngeal, head and neck, oesophageal squamous cell carcinoma and bladder) diagnosed in England between 2000 and 2014 were obtained from Public Health England National Cancer Registration and Analysis Service. We calculated absolute incidence rates and standardised incidence rate ratios, both overall and for various subgroups of second primary cancer for up to 10

SUBMITTER: Barclay ME 

PROVIDER: S-EPMC6475108 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature