Five-Year Follow-up of Nonfibrotic Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials.

ABSTRACT:

Purpose

To describe changes in visual acuity (VA) and macular morphologic features at 5 years in eyes with nonfibrotic scar (NFS) identified at 1 year in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).

Design

Prospective cohort study within a randomized clinical trial.

Participants

Participants in CATT.

Methods

Participants assigned to ranibizumab or bevacizumab and to 1 of 3 dosing regimens were released from the clinical trial protocol after 2 years and recalled at 5 years. Nonfibrotic scar was identified on color images at year 1 as flat, small, well-circumscribed areas of pigmentation with varying degrees of central hypopigmentation without exposure of underlying choroidal vessels at the site of baseline choroidal neovasculariza

SUBMITTER: Daniel E 

PROVIDER: S-EPMC6475610 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature