The Diagnostic and Prognostic Value of miR-200c in Gastric Cancer: A Meta-Analysis.

ABSTRACT:

Background

The role of miR-200c in gastric cancer remains controversial. This study is aimed at clarifying the diagnostic and prognostic value of miR-200c in gastric cancer through a meta-analysis.

Methods

A comprehensive literature search of PubMed, Embase, and Ovid library databases was conducted. The studies included were those conducted before December 2017. The sensitivity and specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under curve (AUC) were used to estimate the diagnostic value of miR-200c. Meanwhile, the pooled hazard ratio (HR) was used to estimate the prognostic value of miR-200c.

Results

For the diagnostic value of miR-200c, six studies that included 202 patients with gastric cancer an

SUBMITTER: Huang ZS 

PROVIDER: S-EPMC6476052 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature