High prevalence of fluoroquinolone-resistant Escherichia coli strains isolated from urine clinical samples.

ABSTRACT:

Background

Fluoroquinolone resistant Escherichia coli isolates have become an important challenge in healthcare settings in Iran. In this study, we have determined Fluoroquinolone resistant E. coli isolates (from both outpatients and inpatients) and evaluated mutations of gyrA and parC within the quinolone resistance-determining regions (QRDR) of these clinical isolates.

Materials and methods

Clinical isolates were recovered from the urine sample of patients with urinary tract infections admitted at Alzahra hospital, Iran, between September and February 2013. We assessed antimicrobial susceptibility of all isolates and determined mutations in QRDR of gyrA and parC genes from 13 fluoroquinolone-resistant isolates by DNA sequencing.

Results

A total of 135 E. coli strain

SUBMITTER: Dehbanipour R 

PROVIDER: S-EPMC6477561 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature