Pharmacotherapy for hyperuricemia in hypertensive patients.

ABSTRACT:

Background

High blood pressure represents a major public health problem. Worldwide, approximately one-fourth of the adult population has hypertension. Epidemiological and experimental studies suggest a link between hyperuricemia and hypertension. Hyperuricemia affects 25% to 40 % of individuals with untreated hypertension; a much lower prevalence has been reported in normotensives or in the general population. However, whether lowering serum uric acid (UA) might lower blood pressure (BP) is an unanswered question.

Objectives

To determine whether UA-lowering agents reduce BP in patients with primary hypertension or prehypertension compared with placebo.

Search methods

The Cochrane Hypertension Information Specialist searched the following databases for randomized contr

SUBMITTER: Gois PHF 

PROVIDER: S-EPMC6478066 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature