Dataset Information
Blood pressure lowering efficacy of renin inhibitors for primary hypertension.
Ontology highlight
ABSTRACT:
SUBMITTER: Musini VM
PROVIDER: S-EPMC6478238 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Publications
Blood pressure lowering efficacy of renin inhibitors for primary hypertension.
The Cochrane database of systematic reviews 20170405
<h4>Background</h4>Hypertension is a chronic condition associated with an increased risk of mortality and morbidity. Renin is the enzyme responsible for converting angiotensinogen to angiotensin I, which is then converted to angiotensin II. Renin inhibitors are a new class of drugs that decrease blood pressure (BP) by preventing the formation of both angiotensin I and angiotensin II.<h4>Objectives</h4>To quantify the dose-related BP lowering efficacy of renin inhibitors compared to placebo in th ...[more]