A Longitudinal Study of Ebola Sequelae in Liberia.

ABSTRACT:

Background

Multiple health problems have been reported in survivors of Ebola virus disease (EVD). Attribution of these problems to the disease without a control group for analysis is difficult.

Methods

We enrolled a cohort of EVD survivors and their close contacts and prospectively collected data on symptoms, physical examination findings, and laboratory results. A subset of participants underwent ophthalmologic examinations. Persistence of Ebola virus (EBOV) RNA in semen samples from survivors was determined.

Results

A total of 966 EBOV antibody-positive survivors and 2350 antibody-negative close contacts (controls) were enrolled, and 90% of these participants were followed for 12 months. At enrollment (median time to baseline visit, 358 days after symptom onset), si

SUBMITTER: PREVAIL III Study Group 

PROVIDER: S-EPMC6478393 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature