Ontology highlight
ABSTRACT:
SUBMITTER: Du B
PROVIDER: S-EPMC6478710 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Du Biao B Huang Zhengsong Z Wang Xiao X Chen Ting T Shen Guo G Fu Shaomin S Liu Bo B
Nature communications 20190423 1
The dimeric lindenane sesquiterpenoids are mainly isolated from the plants of Chloranthaceae family. Structurally, they have a crowded molecular scaffold decorated with more than 11 stereogenic centers. Here we report divergent syntheses of eight dimeric lindenane sesquiterpenoids, shizukaols A, C, D, I, chlorajaponilide C, multistalide B, sarcandrolide J and sarglabolide I. In particular, we present a unified dimerization strategy utilizing a base-mediated thermal [4 + 2] cycloaddition between ...[more]