New Dammarane-type Saponins from Gynostemma pentaphyllum.

ABSTRACT: Six new dammarane-type saponins, gypenosides CP1-6 (16), along with 19 known compounds 7⁻25, were isolated and characterized from the aerial parts of Gynostemma pentaphyllum. Among these compounds, eight dammarane-type saponins, 2, 5, 6, 7, 11, 12, 13, and 15, exhibited the greatest antiproliferative effects against two human tumor cell lines (A549 and HepG2).

SUBMITTER: Chen PY 

PROVIDER: S-EPMC6480664 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature