Properties of Poly-γ-Glutamic Acid Producing-Bacillus Species Isolated From Ogi Liquor and Lemon-Ogi Liquor.

ABSTRACT: Poly-γ-glutamic acid (γPGA) is a natural and promising biopolymer synthesized by Bacillus spp. during fermentation. This study isolated Bacillus spp. from ogi steep liquor (OSL) and lemon-ogi steep liquor (LOSL) using standard methods and determined the γPGA-producing ability. The antimicrobial and angiotensin-converting enzyme (ACE) inhibitory activities of γPGA polymer were evaluated and isolates were sequenced. Four isolates (TA004, TA006, TA011, TA012) selected based on phenotypic characterization and stickiness (<15 cm) showed antibacterial activity against different pathogens with the highest activity found in TA004 (22.5 mm) and least in TA011 (16.6 mm). Furthermore, time-kill assay showed that the combined γPGA polymer was more effective and demonstrated

SUBMITTER: Ajayeoba TA 

PROVIDER: S-EPMC6481274 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature