Single dose oral ibuprofen plus caffeine for acute postoperative pain in adults.

ABSTRACT:

Background

There is good evidence that combining two different analgesics in fixed doses in a single tablet can provide better pain relief in acute pain and headache than either drug alone, and that the drug-specific benefits are essentially additive. This appears to be broadly true in postoperative pain and migraine headache across a range of different drug combinations, and when tested in the same and different trials. Adding caffeine to analgesics also increases the number of people obtaining good pain relief. Combinations of ibuprofen and caffeine are available without prescription in some parts of the world.

Objectives

To assess the analgesic efficacy and adverse effects of a single oral dose of ibuprofen plus caffeine for moderate to severe postoperative pain, using me

SUBMITTER: Derry S 

PROVIDER: S-EPMC6481458 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature