Growth factors for angiogenesis in peripheral arterial disease.
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ABSTRACT:
SUBMITTER: Gorenoi V
PROVIDER: S-EPMC6481523 | biostudies-literature | 2017 Jun
REPOSITORIES: biostudies-literature
Publications
Growth factors for angiogenesis in peripheral arterial disease.
Gorenoi Vitali V Brehm Michael U MU Koch Armin A Hagen Anja A
The Cochrane database of systematic reviews 20170608
<h4>Background</h4>Peripheral artery disease (PAD) is associated with a high clinical and socioeconomic burden. Treatments to alleviate the symptoms of PAD and decrease the risks of amputation and death are a high societal priority. A number of growth factors have shown a potential to stimulate angiogenesis. Growth factors delivered directly (as recombinant proteins), or indirectly (e.g. by viral vectors or DNA plasmids encoding these factors), have emerged as a promising strategy to treat patie ...[more]
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