Outcomes of Cutaneous Squamous Cell Carcinoma in the Head and Neck Region With Regional Lymph Node Metastasis: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

There is a need to summarize the available evidence and provide quantitative data of the most important prognostic factors for patients with metastatic cutaneous squamous cell carcinoma of the head and neck region with regional lymph node metastasis (McSCCHN).

Objective

To undertake a PRISMA-compliant systematic review and meta-analysis of all published studies on the risk factors for overall survival (OS), locoregional control (LRC), locoregional recurrence (LRR), and disease-specific survival (DSS) for patients with McSCCHN.

Data sources

PubMed, CINAHL, and Embase were searched from 1946 to August 2018 for English-language articles.

Study selection

Inclusion criteria were randomized clinical trials or observational studies reporting on at least 10

SUBMITTER: Sahovaler A 

PROVIDER: S-EPMC6481593 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature