Transcranial Doppler ultrasound in vascular cognitive impairment-no dementia.

ABSTRACT:

Background

Although cerebral white matter lesions (WMLs) are considered as a risk factor for vascular dementia, data on their impact on cerebral hemodynamics are scarce. We test and compare transcranial Doppler (TCD) features in WML patients with or without associated cognitive impairment.

Methods

A sample of non-demented elderly patients with WMLs was consecutively recruited. Mean blood flow velocity (MBFV), pulsatility index (PI), peak systolic blood flow velocity (PSV), end-diastolic blood flow velocity (EDV), and resistivity index (RI) were recorded from the middle cerebral artery bilaterally. Global cognitive functioning, frontal lobe abilities, functional status, and WML severity were also assessed.

Results

161 patients satisfying the clinical criteria for vascu

SUBMITTER: Vinciguerra L 

PROVIDER: S-EPMC6481922 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature