Distress and quality of life in patient and caregiver dyads facing stem cell transplant: identifying overlap and unique contributions.

ABSTRACT:

Purpose

Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a demanding treatment requiring caregiver support. The pre-transplant period is particularly stressful. How patient and caregiver dyads respond to these stressors can impact post-transplant outcomes. The purpose of this cross-sectional study was to assess pre-transplant patient and caregiver distress, patient quality of life (pQoL), and simultaneously investigate relationship between caregiver distress, patient distress, and patient QoL.

Methods

We measured caregiver anxiety, depressive symptoms, perceived stress, sleep quality, caregiver burden, and pQoL in148 dyads compared to clinical thresholds or population norms. To reduce comparisons, we created a composite distress score from affective measures

SUBMITTER: Sannes TS 

PROVIDER: S-EPMC6482095 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature