Sensing Glucose in the Central Melanocortin Circuits of Rainbow Trout: A Morphological Study.

ABSTRACT: In mammals, glucosensing markers reside in brain areas known to play an important role in the control of food intake. The best characterized glucosensing mechanism is that dependent on glucokinase (GK) whose activation by increased levels of glucose leads in specific hypothalamic neurons to decreased or increased activity, ultimately leading to decreased food intake. In fish, evidence obtained in recent years suggested the presence of GK-like immunoreactive cells in different brain areas related to food intake control. However, it has not been established yet whether or not those neuronal populations having glucosensing capacity are the same that express the neuropeptides involved in the metabolic control of food intake. Therefore, we assessed through dual fluorescent in situ hybrid

SUBMITTER: Otero-Rodino C 

PROVIDER: S-EPMC6482260 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature