Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy.
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ABSTRACT:
SUBMITTER: Riley P
PROVIDER: S-EPMC6483146 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Publications
Pharmacological interventions for preventing dry mouth and salivary gland dysfunction following radiotherapy.
Riley Philip P Glenny Anne-Marie AM Hua Fang F Worthington Helen V HV
The Cochrane database of systematic reviews 20170731
<h4>Background</h4>Salivary gland dysfunction is an 'umbrella' term for the presence of either xerostomia (subjective sensation of dryness), or salivary gland hypofunction (reduction in saliva production). It is a predictable side effect of radiotherapy to the head and neck region, and is associated with a significant impairment of quality of life. A wide range of pharmacological interventions, with varying mechanisms of action, have been used for the prevention of radiation-induced salivary gla ...[more]
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