Ontology highlight
ABSTRACT:
SUBMITTER: Divakaruni SS
PROVIDER: S-EPMC6483400 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Divakaruni Sai Sachin SS Van Dyke Adam M AM Chandra Ramesh R LeGates Tara A TA Contreras Minerva M Dharmasri Poorna A PA Higgs Henry N HN Lobo Mary Kay MK Thompson Scott M SM Blanpied Thomas A TA
Neuron 20181011 4
Synaptic transmission is bioenergetically demanding, and the diverse processes underlying synaptic plasticity elevate these demands. Therefore, mitochondrial functions, including ATP synthesis and Ca<sup>2+</sup> handling, are likely essential for plasticity. Although axonal mitochondria have been extensively analyzed, LTP is predominantly induced postsynaptically, where mitochondria are understudied. Additionally, though mitochondrial fission is essential for their function, signaling pathways ...[more]