Reduced Neural Sensitivity to Social vs Nonsocial Reward in Schizophrenia.

ABSTRACT:

Background

Human beings find social stimuli rewarding, which is thought to facilitate efficient social functioning. Although reward processing has been extensively studied in schizophrenia, a few studies have examined neural processes specifically involved in social reward processing. This study examined neural sensitivity to social and nonsocial rewards in schizophrenia.

Methods

Twenty-seven patients with schizophrenia and 25 community controls completed a One-Armed Bandit Task, an implicit reinforcement learning task, in the scanner. There were 2 conditions with an identical trial structure, one with social rewards and the other with nonsocial rewards. The data were analyzed using a region of interest (ROI) approach, focusing on the ventral striatum, ventromedial prefronta

SUBMITTER: Lee J 

PROVIDER: S-EPMC6483569 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature