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Thrombopoietin mimetics for patients with myelodysplastic syndromes.


ABSTRACT:

SUBMITTER: Dodillet H 

PROVIDER: S-EPMC6483680 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Thrombopoietin mimetics for patients with myelodysplastic syndromes.

Dodillet Helga H   Kreuzer Karl-Anton KA   Monsef Ina I   Skoetz Nicole N  

The Cochrane database of systematic reviews 20170930


<h4>Background</h4>Myelodysplastic syndrome (MDS) is one of the most frequent haematologic malignancies of the elderly population and characterised by progenitor cell dysplasia with ineffective haematopoiesis and a high rate of transformation to acute myeloid leukaemia (AML). Thrombocytopenia represents a common problem for patients with MDS. ranging from mild to serious bleeding events and death. To manage thrombocytopenia, the current standard treatment includes platelet transfusion, unfortuna  ...[more]

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