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Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease.

ABSTRACT:

SUBMITTER: Chong J

PROVIDER: S-EPMC6483682 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature

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Phosphodiesterase 4 inhibitors for chronic obstructive pulmonary disease.

Chong Jimmy J Leung Bonnie B Poole Phillippa P

The Cochrane database of systematic reviews 20170919

<h4>Background</h4>Chronic obstructive pulmonary disease (COPD) is associated with cough, sputum production or dyspnoea and a reduction in lung function, quality of life and life expectancy. Apart from smoking cessation, there are no other treatments that slow lung function decline. Roflumilast and cilomilast are oral phosphodiesterase 4 (PDE<sub>4</sub>) inhibitors proposed to reduce the airway inflammation and bronchoconstriction seen in COPD. This is an update of a Cochrane review first publi ...[more]

PMID: 28922692

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