Visual memory tests enhance the identification of amnestic MCI cases at greater risk of Alzheimer's disease.

ABSTRACT:

Objectives

To investigate whether amnestic mild cognitive impairment (aMCI) identified with visual memory tests conveys an increased risk of Alzheimer's disease (risk-AD) and if the risk-AD differs from that associated with aMCI based on verbal memory tests.

Participants

4,771 participants aged 70.76 (SD = 6.74, 45.4% females) from five community-based studies, each a member of the international COSMIC consortium and from a different country, were classified as having normal cognition (NC) or one of visual, verbal, or combined (visual and verbal) aMCI using international criteria and followed for an average of 2.48 years. Hazard ratios (HR) and individual patient data (IPD) meta-analysis analyzed the risk-AD with age, sex, education, single/multiple domain aMCI, and Mini-Men

SUBMITTER: Oltra-Cucarella J 

PROVIDER: S-EPMC6483891 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature