Ontology highlight
ABSTRACT:
SUBMITTER: Unverzagt S
PROVIDER: S-EPMC6484451 | biostudies-literature | 2017 May
REPOSITORIES: biostudies-literature

The Cochrane database of systematic reviews 20170515
<h4>Background</h4>Since the mid-2000s, the field of metastatic renal cell carcinoma (mRCC) has experienced a paradigm shift from non-specific therapy with broad-acting cytokines to specific regimens, which directly target the cancer, the tumour microenvironment, or both.Current guidelines recommend targeted therapies with agents such as sunitinib, pazopanib or temsirolimus (for people with poor prognosis) as the standard of care for first-line treatment of people with mRCC and mention non-speci ...[more]