Cost-effectiveness Analysis of Bariatric Surgery for Patients With Nonalcoholic Steatohepatitis Cirrhosis.

ABSTRACT:

Importance

Obesity is the most common risk factor for nonalcoholic steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease that can lead to cirrhosis and hepatocellular carcinoma. Weight loss can be an effective treatment for obesity and may slow the progression of advanced liver disease.

Objective

To assess the cost-effectiveness of bariatric surgery in patients with NASH and compensated cirrhosis.

Design, setting, and participants

This economic evaluation study used a Markov-based state-transition model to simulate the benefits and risks of laparoscopic sleeve gastrectomy (SG), laparoscopic Roux-en-Y gastric bypass (GB), and intensive lifestyle intervention (ILI) compared with usual care in patients with NASH and compensated cirrhosis and va

SUBMITTER: Klebanoff MJ 

PROVIDER: S-EPMC6484583 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature