Analysis of Benefit of Intensive Care Unit Transfer for Deteriorating Ward Patients: A Patient-Centered Approach to Clinical Evaluation.

ABSTRACT:

Importance

It is unknown which deteriorating ward patients benefit from intensive care unit (ICU) transfer.

Objectives

To use an instrumental variable (IV) method that assesses heterogeneity and to evaluate estimates of person-centered treatment effects of ICU transfer and 28-day hospital mortality by age and illness severity.

Design, setting, and participants

An analysis of a prospective cohort study from November 1, 2010, to December 31, 2011. The dates of this analysis were June 1, 2017, to June 30, 2018. The setting was a multicenter study of 49 UK National Health Service hospitals. Participants were 9192 deteriorating ward patients assessed for ICU transfer (4596 matched pairs). The study matched on baseline characteristics to strengthen the IV and to balance obs

SUBMITTER: Grieve R 

PROVIDER: S-EPMC6484590 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature