Association of Bone Metastasis With Early-Stage Breast Cancer in Women With and Without Precancer Osteoporosis According to Osteoporosis Therapy Status.

ABSTRACT:

Importance

Deaths from cancer are attributed more to secondary than primary tumors, but the pathogenesis of organ-specific cancer metastasis has not been determined.

Objective

To investigate whether precancer osteoporosis and osteoporosis therapy are associated with alteration of bone metastasis patterns.

Design, setting, and participants

This nationwide retrospective cohort study was performed from January 1, 2002, to December 31, 2013, using 2 cohorts from the Taiwan National Health Insurance Research Database: a random sample of 1 million beneficiaries from the Longitudinal Health Insurance Database who were enrolled in 2005 (LHID2005) and a specific data set of all the patients with osteoporosis. Patients diagnosed with breast cancer and precancer osteoporosis fro

SUBMITTER: Chen HM 

PROVIDER: S-EPMC6484629 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature