Mesalamine (5-ASA) for the prevention of recurrent diverticulitis.

ABSTRACT:

Background

Diverticular disease is a common condition that increases in prevalence with age. Recent theories on the pathogenesis of diverticular inflammation have implicated chronic inflammation similar to that seen in ulcerative colitis. Mesalamine, or 5-aminosalicylic acid (5-ASA), is a mainstay of therapy for individuals with ulcerative colitis. Accordingly, 5-ASA has been studied for prevention of recurrent diverticulitis.

Objectives

To evaluate the efficacy of mesalamine (5-ASA) for prevention of recurrent diverticulitis.

Search methods

We searched the Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 8), in the Cochrane Library; Ovid MEDLINE (from 1950 to 9 September 2017); Ovid Embase (from 1974 to 9 September 2017); and two clinical trials r

SUBMITTER: Carter F 

PROVIDER: S-EPMC6485423 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature