Age-related differences in water and sodium handling after commercial hydration beverage ingestion.

ABSTRACT: Aging is associated with altered water, electrolyte, and glucose handling. Alternative beverages to those containing carbohydrate (CHO) should be considered for older adults. We hypothesized that reduced sodium (CNa⁺) and/or water (CH₂O) clearance would underlie greater beverage retention in older compared with young adults, secondary to reduced glomerular filtration rate (GFR). We further hypothesized that amino acid (AA)- and CHO-based beverages would promote retention better than water. Over five visits, 12 young (23 ± 3 yr; 7 men, 5 women) and 12 older (67 ± 6 yr; 5 men, 7 women) subjects consumed 1 liter of distilled water or beverages with 6% CHO, 0.46 g/l Na⁺ [Gatorade (GAT)]; 2.5% CHO, 0.74 g/l Na⁺ [Pedialyte (PED)]; 5 AA, 1.04 g/l Na

SUBMITTER: Wolf ST 

PROVIDER: S-EPMC6485687 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature