Bisphosphonates for Paget's disease of bone in adults.
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ABSTRACT:
SUBMITTER: Corral-Gudino L
PROVIDER: S-EPMC6486234 | biostudies-literature | 2017 Dec
REPOSITORIES: biostudies-literature
Publications
Bisphosphonates for Paget's disease of bone in adults.
Corral-Gudino Luis L Tan Adrian Jh AJ Del Pino-Montes Javier J Ralston Stuart H SH
The Cochrane database of systematic reviews 20171201
<h4>Background</h4>Bisphosphonates are considered to be the treatment of choice for people with Paget's disease of bone. However, the effects of bisphosphonates on patient-centred outcomes have not been extensively studied. There are insufficient data to determine whether reducing and maintaining biochemical markers of bone turnover to within the normal range improves quality of life and reduces the risk of complications.<h4>Objectives</h4>To assess the benefits and harms of bisphosphonates for ...[more]
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