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Bisphosphonates for advanced prostate cancer.


ABSTRACT:

SUBMITTER: Macherey S 

PROVIDER: S-EPMC6486306 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature

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Bisphosphonates for advanced prostate cancer.

Macherey Sascha S   Monsef Ina I   Jahn Franziska F   Jordan Karin K   Yuen Kwok Keung KK   Heidenreich Axel A   Skoetz Nicole N  

The Cochrane database of systematic reviews 20171226


<h4>Background</h4>The prevalence and incidence of pain and skeletal complications of metastatic bone disease such as pathologic fractures, spinal cord compression and hypercalcemia is high and an important contributor to morbidity, poor performance status and decreased quality of life. Moreover, pathologic fractures are associated with increased risk of death in people with disseminated malignancies. Therefore, prevention of pain and fractures are important goals in men with prostate cancer at  ...[more]

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