Discordance in Antenatal Corticosteroid Use and Resuscitation Following Extremely Preterm Birth.

ABSTRACT:

Objective

To describe discordance in antenatal corticosteroid use and resuscitation following extremely preterm birth and its relationship with infant survival and neurodevelopment.

Study design

A multicenter cohort study of 4858 infants 22-26 weeks of gestation born 2006-2011 at 24 US hospitals participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, with follow-up through 2013. Survival and neurodevelopmental outcomes were available at 18-22 months of corrected age for 4576 (94.2%) infants. We described antenatal interventions, resuscitation, and infant outcomes. We modeled the effect on infant outcomes of each hospital increasing antenatal corticosteroid exposure for resuscitated infants born at 22-24 

SUBMITTER: Rysavy MA 

PROVIDER: S-EPMC6486854 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature