Post-viral atopic airway disease: pathogenesis and potential avenues for intervention.

ABSTRACT: Introduction: In early childhood, wheezing due to lower respiratory tract illness is often associated with infection by commonly known respiratory viruses such as respiratory syncytial virus (RSV) and human rhinovirus (RV). How respiratory viral infections lead to wheeze and/or asthma is an area of active research. Areas covered: This review provides an updated summary of the published information on the development of post-viral induced atopy and asthma and the mechanisms involved. We focus on the contribution of animal models in identifying pathways that may contribute to atopy and asthma following respiratory virus infection, different polymorphisms that have been associated with asthma development, and current options for disease management and potential future interventi

SUBMITTER: Hussain SA 

PROVIDER: S-EPMC6486879 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature