DNAscan: personal computer compatible NGS analysis, annotation and visualisation.

ABSTRACT:

Background

Next Generation Sequencing (NGS) is a commonly used technology for studying the genetic basis of biological processes and it underpins the aspirations of precision medicine. However, there are significant challenges when dealing with NGS data. Firstly, a huge number of bioinformatics tools for a wide range of uses exist, therefore it is challenging to design an analysis pipeline. Secondly, NGS analysis is computationally intensive, requiring expensive infrastructure, and many medical and research centres do not have adequate high performance computing facilities and cloud computing is not always an option due to privacy and ownership issues. Finally, the interpretation of the results is not trivial and most available pipelines lack the utilities to favour this crucial st

SUBMITTER: Iacoangeli A 

PROVIDER: S-EPMC6487045 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature